Hydrochlorothiazide and Hypertension: Why is it so popular among cardiologists?

Hydrochlorothiazide is a medication widely used in cardiology primarily for the treatment of hypertension, though it also has a role in heart failure. It belongs to the thiazide group, sharing the stage with other excellent medications such as chlorthalidone and indapamide.

Why is it so widely used? It is a medication that was approved by the FDA in the 1960s for the treatment of hypertension and edema in the lower limbs. It has been extensively proven to be safe, highly effective, and currently very economical in its generic form.

What are its effects? It is a diuretic, meaning it works at the renal level by increasing the elimination of sodium and water. This mechanism helps excrete excess fluid in the body and also has a vasodilatory effect. It is a slow-acting and gradual medication, so once treatment is started, you should wait at least 5 days to achieve its full effect.

How effective is it? It has been shown to reduce cardiovascular events due to its potency against high blood pressure in multiple clinical trials. It is mainly used as a complementary drug and in low doses in the treatment of hypertension, along with ACE inhibitors (e.g., Enalapril) or ARBs (e.g., Losartan).

What is the dosage and how should I take it? The dose ranges from 12.5 mg to 50 mg once a day. It is taken once a day, and food does not affect its absorption.

🩺 Of course, it is important for each patient to consult their cardiologist to review the details and obtain the best treatment for their cardiovascular condition.

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